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Antimicrobial resistance

    Overview

    Antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi.

    AMR occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death. As a result, the medicines become ineffective and infections persist in the body, increasing the risk of spread to others.

    Antimicrobials - including antibiotics, antivirals, antifungals and antiparasitics - are medicines used to prevent and treat infections in humans, animals and plants. Microorganisms that develop antimicrobial resistance are sometimes referred to as “superbugs”.

    News

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    WHO and the European Commission expand partnership to combat antimicrobial resistance

    Dec 10, 2025, 08:59 AM
    The World Health Organization (WHO) and the European Commission’s Health Emergency Preparedness Authority (HERA) have signed a €3.5 million agreement to expand their partnership to combat antimicrobial resistance under the EU4Health programme. The new funding agreement will enable WHO to scale up work on research and development for new antibiotics, antifungals, and non-traditional therapies such as bacteriophages which use viruses to infect and kill bacteria. WHO will also enhance the SECURE initiative, co-led with the Global Antibiotic Research & Development Partnership (GARDP), to improve sustainable access to new and existing antibiotics worldwide.

    The World Health Organization (WHO) and the European Commission’s Health Emergency Preparedness Authority (HERA) have signed a €3.5 million agreement to expand their partnership to combat antimicrobial resistance under the EU4Health programme.

    The new funding agreement will enable WHO to scale up work on research and development for new antibiotics, antifungals, and non-traditional therapies such as bacteriophages which use viruses to infect and kill bacteria. WHO will also enhance the SECURE initiative, co-led with the Global Antibiotic Research & Development Partnership (GARDP), to improve sustainable access to new and existing antibiotics worldwide.

    “Antimicrobial resistance is one of the most urgent threats to global health and security,” said Dr Yvan Hutin, Director of Antimicrobial Resistance at WHO. “WHO welcomes this renewed partnership with the European Commission to accelerate efforts to fight AMR by ensuring equitable access to life-saving antimicrobials and diagnostics for people everywhere.”

    Recognizing AMR as a major and growing health threat, WHO and HERA first launched the partnership in 2022 to support the development of new medical countermeasures for tackling AMR and ensure their equitable access. Since then, the partnership has focused on advancing new antibiotics capable of combating the most dangerous drug-resistant pathogens.

    Through funding by HERA, WHO has published the updated Bacterial Priority Pathogens List (BPPL) and advanced implementation of the first Fungal Priority Pathogens List (FPPL) through global expert consultations and regional workshops. The Organization has also published multiple R&D pipeline assessments in the areas of antibacterials, antifungals and in vitro diagnostics for bacterial and fungal pathogens, respectively, and has advanced work to accelerate optimal approval of priority formulations for pediatric antibiotics.

    Additionally, WHO has also advanced work on SECURE through a global technical consultation and the development of WHO Country Operational Guidance for introducing antibiotics as well as guidance on policy and regulatory interventions to address antibiotic shortages. These efforts have strengthened global awareness of AMR, informed R&D priorities, and laid foundation for improved access to life-saving treatments in low- and middle-income countries.

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    Our work

    Documents

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    This guidance note explains the importance of including activities for antimicrobial resistance (AMR) surveillance and laboratory strengthening into proposals...

    Thumbnail for Global Call to Action to address AMR

    Antimicrobial resistance (AMR) is one of the greatest global health threats of our time, undermining our ability to treat infections and deliver safe medical...

    Country profiles

    Country profiles

    Country profiles present selected data, statistics and information to provide national health profiles at given points in time.
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